Radiotherapy Research Today is a free monthly online journal that collates and summarizes the latest research about Radiotherapy, including details on cancer treatment, side effects.

What is the best adjuvant treatment for very young patients with medulloblastoma?

Clarke JW, Hadziahmetovic M, Tzou K, Lau CC, Paulino AC, Grecula JC, Montebello JF, Mayr NA, Lo SS

Ohio State University Medical Center, Department of Radiation Medicine, Arthur G James Cancer Hospital, Columbus, OH 43210, USA. james.clarke@osumc.edu

The standard treatment for medulloblastoma is surgery followed by adjuvant chemotherapy and external beam radiotherapy to the craniospinal axis and posterior fossa. However, in very young children, craniospinal irradiation has a more significant detrimental effect in terms of neurocognitive function and growth. This article reviews the different strategies used for very young patients with medulloblastoma.

Published 11 April 2007 in Expert Rev Neurother, 7(4): 373-81.
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