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Oncocytic meningioma: report of a case with progression after radiosurgery.

Marucci G, Betts CM, Frank G, Foschini MP

Anatomic Pathology, University of Bologna, Bellaria Hospital, Bologna, Italy.

Oncocytic meningioma is an uncommon variant of meningioma, characterized histologically by cells rich in mitochondria. This subtype of meningioma needs to be distinguished from other types of meningioma because of its more aggressive behavior. A case of oncocytic meningioma showing rapid clinical progression with diffuse intracranial dissemination after radiosurgery is described. Resistance to radiotherapy has been previously reported in oncocytic tumors of various body sites. This new case is a further example of the greater aggressiveness of oncocytic meningioma, suggesting that radiation therapy might worsen the course of disease.

Published 18 December 2006 in Int J Surg Pathol, 15(1): 77-81.
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